🌿 Written by the Olicept Wellness Desk📅 Updated October 2026✅ Structure-function wording · unknown facts are labelled
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St. John's Wort And Medicine Interactions

By the Olicept Wellness Desk · Updated October 2026
In short: St. John's wort can interact with antidepressants, blood thinners, contraceptives and many other medicines. Ask a pharmacist before using it.

Why It Interacts

St. John's wort can speed up the liver enzymes that clear many medicines, which can make them less effective. It can also add to serotonin effects of antidepressants.

Medicines Of Concern

Antidepressants, warfarin and other blood thinners, hormonal contraceptives, some heart, cancer, transplant and HIV medicines, among others.

Other Effects

It may increase sun sensitivity and can cause stomach upset, dizziness or tiredness in some people.

What To Do

Bring your full medicine list to a pharmacist before using any product that contains it. Never stop a prescription to take a supplement. See our safety guide.

Key Takeaways

Learn more on our ingredients page or read the honest review.

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